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Preclinical Evidence That Activation of Mesolimbic Alpha 6 Subunit Containing Nicotinic Acetylcholine Receptors Supports Nicotine Addiction Phenotype

INTRODUCTION: Nicotine is a major psychoactive ingredient in tobacco yet very few individuals quit smoking with the aid of nicotine replacement therapy. Targeted therapies with more selective action at nicotinic acetylcholine receptors (nAChRs) that contain a β2 subunit (β2*nAChRs; *denotes assembly...

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Detalles Bibliográficos
Autor principal: Brunzell, Darlene H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482009/
https://ncbi.nlm.nih.gov/pubmed/22492084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/nts089
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