Alpha7 Nicotinic Acetylcholine Receptors Modulate Motivation to Self-Administer Nicotine: Implications for Smoking and Schizophrenia

Individuals diagnosed with schizophrenia have an exceptionally high risk for tobacco dependence. Postmortem studies show that these individuals have significant reductions in α7 nicotinic acetylcholine receptors (nAChRs) in several brain areas. Decreased α7-mediated function might not only be linked...

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Bibliographic Details
Main Authors: Brunzell, Darlene H, McIntosh, J Michael
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306875/
https://ncbi.nlm.nih.gov/pubmed/22169946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.299
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