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Alpha7 Nicotinic Acetylcholine Receptors Modulate Motivation to Self-Administer Nicotine: Implications for Smoking and Schizophrenia

Individuals diagnosed with schizophrenia have an exceptionally high risk for tobacco dependence. Postmortem studies show that these individuals have significant reductions in α7 nicotinic acetylcholine receptors (nAChRs) in several brain areas. Decreased α7-mediated function might not only be linked...

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Detalhes bibliográficos
Main Authors: Brunzell, Darlene H, McIntosh, J Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306875/
https://ncbi.nlm.nih.gov/pubmed/22169946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.299
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