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It's not “either/or”: activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood

Nicotine can both activate and desensitize/inactivate nicotinic acetylcholine receptors (nAChRs). An ongoing controversy in the field is to what extent the behavioral effects of nicotine result from activation of nAChRs, and to what extent receptor desensitization is involved in these behavioral pro...

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Detalhes bibliográficos
Main Authors: Picciotto, Marina R., Addy, Nii A., Mineur, Yann S., Brunzell, Darlene H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390914/
https://ncbi.nlm.nih.gov/pubmed/18242816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2007.12.005
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