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It's not “either/or”: activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood

Nicotine can both activate and desensitize/inactivate nicotinic acetylcholine receptors (nAChRs). An ongoing controversy in the field is to what extent the behavioral effects of nicotine result from activation of nAChRs, and to what extent receptor desensitization is involved in these behavioral pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Picciotto, Marina R., Addy, Nii A., Mineur, Yann S., Brunzell, Darlene H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390914/
https://ncbi.nlm.nih.gov/pubmed/18242816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2007.12.005
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