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Preclinical Evidence That Activation of Mesolimbic Alpha 6 Subunit Containing Nicotinic Acetylcholine Receptors Supports Nicotine Addiction Phenotype

INTRODUCTION: Nicotine is a major psychoactive ingredient in tobacco yet very few individuals quit smoking with the aid of nicotine replacement therapy. Targeted therapies with more selective action at nicotinic acetylcholine receptors (nAChRs) that contain a β2 subunit (β2*nAChRs; *denotes assembly...

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Autor principal: Brunzell, Darlene H.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482009/
https://ncbi.nlm.nih.gov/pubmed/22492084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/nts089
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