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Effect of inhibition of the Ubiquitin-Proteasome System and Hsp90 on growth and survival of Rhabdomyosarcoma cells in vitro

BACKGROUND: The ubiquitin-proteasome system (UPS) and the heat shock response (HSR) are two critical regulators of cell homeostasis, as their inhibition affects growth and survival of normal cells, as well as stress response and invasiveness of cancer cells. We evaluated the effects of the proteasom...

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Detalhes bibliográficos
Main Authors: Peron, Marica, Bonvini, Paolo, Rosolen, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480867/
https://ncbi.nlm.nih.gov/pubmed/22691173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-233
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