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Effect of inhibition of the Ubiquitin-Proteasome System and Hsp90 on growth and survival of Rhabdomyosarcoma cells in vitro

BACKGROUND: The ubiquitin-proteasome system (UPS) and the heat shock response (HSR) are two critical regulators of cell homeostasis, as their inhibition affects growth and survival of normal cells, as well as stress response and invasiveness of cancer cells. We evaluated the effects of the proteasom...

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Sonraí Bibleagrafaíochta
Main Authors: Peron, Marica, Bonvini, Paolo, Rosolen, Angelo
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480867/
https://ncbi.nlm.nih.gov/pubmed/22691173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-233
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