Inhibition of HSP90β Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System

Rationale: Heat shock protein 9 (HSP90) are a family of the most highly expressed cellular proteins and attractive drug targets against cancer, neurodegeneration diseases, etc. HSP90 proteins have also been suggested to be linked to lipid metabolism. However, the specific function of HSP90 paralogs,...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zheng, Zu-Guo, Zhang, Xin, Liu, Xiao-Xiao, Jin, Xiu-Xiu, Dai, Lunzhi, Cheng, Hui-Min, Jing, Dan, Thu, Pyone Myat, Zhang, Mu, Li, Hongyang, Zhu, Jing, Liu, Chang, Xue, Bin, Li, Yu, Chen, Ligong, Peng, Cheng, Zhu, Weiliang, Wang, Lin, Liu, Junli, Li, Hui-Jun, Li, Ping, Xu, Xiaojun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735373/
https://ncbi.nlm.nih.gov/pubmed/31534518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.36505
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