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Effect of inhibition of the Ubiquitin-Proteasome System and Hsp90 on growth and survival of Rhabdomyosarcoma cells in vitro

BACKGROUND: The ubiquitin-proteasome system (UPS) and the heat shock response (HSR) are two critical regulators of cell homeostasis, as their inhibition affects growth and survival of normal cells, as well as stress response and invasiveness of cancer cells. We evaluated the effects of the proteasom...

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Autors principals: Peron, Marica, Bonvini, Paolo, Rosolen, Angelo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480867/
https://ncbi.nlm.nih.gov/pubmed/22691173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-233
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