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Function of carbonic anhydrase IX in glioblastoma multiforme
Carbonic anhydrase (CA) IX is over-expressed in glioblastoma; however, its functions in this context are unknown. Metabolically, glioblastomas are highly glycolytic, leading to a significant lactic acid load. Paradoxically, the intracellular pH is alkaline. We hypothesized that CAIX contributes to t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480266/ https://ncbi.nlm.nih.gov/pubmed/23074198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos216 |
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