Expression of hypoxia-inducible carbonic anhydrases in brain tumors

Malignant brain tumors exhibit distinct metabolic characteristics. Despite high levels of lactate, the intracellular pH of brain tumors is more alkaline than normal brain. Additionally, with increasing malignancy, brain tumors display intratumoral hypoxia. Carbonic anhydrase (CA) IX and XII are tran...

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Detalhes bibliográficos
Main Authors: Proescholdt, Martin A., Mayer, Christina, Kubitza, Marion, Schubert, Thomas, Liao, Shu-Yuan, Stanbridge, Eric J., Ivanov, Sergey, Oldfield, Edward H., Brawanski, Alexander, Merrill, Marsha J.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2005
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871734/
https://ncbi.nlm.nih.gov/pubmed/16212811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851705000025
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