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DDRE-13. INHIBITION OF EXTRACELLULAR CARBONIC ANHYDRASES INHIBITS GLIOBLASTOMA CELL INVASION

OBJECTIVE: Malignant gliomas metabolize glucose preferably by glycolysis which is in accordance with the Warburg effect. This induces a high demand of glucose combined with a significant lactic acid load. The hypoxia-inducible carbonic anhydrase (CA) IX has been shown to moderate the extrusion of hy...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neurooncol Adv
Main Authors: Proescholdt, Martin, Zhenwei, Qiu, Annette, Lohmeier, Nils-Ole, Schmidt, Marsha, Merrill
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992214/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.035
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