Efficacy of D,L-methadone in the treatment of glioblastoma in vitro

AIM: Recently, D,L-methadone has been put forward as adjuvant treatment in glioblastoma (GBM). METHODS: We analyzed the μ-opioid receptor expression in a set of GBM cell lines and investigated the efficacy of D,L-methadone alone and in combination with temozolomide (TMZ). RESULTS & CONCLUSION: E...

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Vydáno v:CNS Oncol
Hlavní autoři: Brawanski, Konstantin, Brockhoff, Gero, Hau, Peter, Vollmann-Zwerenz, Arabel, Freyschlag, Christian, Lohmeier, Annette, Riemenschneider, Markus J, Thomé, Claudius, Brawanski, Alexander, Proescholdt, Martin A
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Medicine Ltd 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200059/
https://ncbi.nlm.nih.gov/pubmed/29916277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns-2018-0006
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