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α-Synuclein disrupts stress signaling by inhibiting polo-like kinase Cdc5/Plk2
Parkinson disease (PD) results from the slow, progressive loss of dopaminergic neurons in the substantia nigra. Alterations in α-synuclein (aSyn), such as mutations or multiplications of the gene, are thought to trigger this degeneration. Here, we show that aSyn disrupts mitogen-activated protein ki...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479570/ https://ncbi.nlm.nih.gov/pubmed/22988096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206286109 |
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