Lataa...
Targeting a pre-mRNA structure with bipartite antisense molecules modulates tau alternative splicing
Approximately 15% of human genetic diseases are estimated to involve dysregulation of alternative pre-mRNA splicing. Antisense molecules designed to alter these and other splicing events typically target continuous linear sequences of the message. Here, we show that a structural feature in a pre-mRN...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2012
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479178/ https://ncbi.nlm.nih.gov/pubmed/22844088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks710 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|