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Mechanism of Transcription Initiation at an Activator-Dependent Promoter Defined by Single-Molecule Observation
Understanding the pathway and kinetic mechanisms of transcription initiation is essential for quantitative understanding of gene regulation, but initiation is a multistep process, the features of which can be obscured in bulk analysis. We used a multiwavelength single-molecule fluorescence colocaliz...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479156/ https://ncbi.nlm.nih.gov/pubmed/22341441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.018 |
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