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Rocket launcher mechanism of collaborative actin assembly defined by single-molecule imaging
Interacting sets of actin assembly factors work together in cells, but the underlying mechanisms have remained obscure. We used triple-color single molecule fluorescence microscopy to image the tumor-suppressor Adenomateous polyposis coli (APC) and the formin mDia1 during filament assembly. Complexe...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613992/ https://ncbi.nlm.nih.gov/pubmed/22654058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1218062 |
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