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Rocket launcher mechanism of collaborative actin assembly defined by single-molecule imaging

Interacting sets of actin assembly factors work together in cells, but the underlying mechanisms have remained obscure. We used triple-color single molecule fluorescence microscopy to image the tumor-suppressor Adenomateous polyposis coli (APC) and the formin mDia1 during filament assembly. Complexe...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Breitsprecher, Dennis, Jaiswal, Richa, Bombardier, Jeffrey P., Gould, Christopher J., Gelles, Jeff, Goode, Bruce L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613992/
https://ncbi.nlm.nih.gov/pubmed/22654058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1218062
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