Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization

Cellular actin networks grow by ATP-actin addition at filament barbed ends and have long been presumed to depolymerize at their pointed ends, primarily after filaments undergo “aging” (ATP hydrolysis and P(i) release). The cytosol contains high levels of actin monomers, which favors assembly over di...

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Bibliografische gegevens
Gepubliceerd in:J Cell Biol
Hoofdauteurs: Shekhar, Shashank, Hoeprich, Gregory J., Gelles, Jeff, Goode, Bruce L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Rockefeller University Press 2020
Onderwerpen:
Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686915/
https://ncbi.nlm.nih.gov/pubmed/33226418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006022
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