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Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization
Cellular actin networks grow by ATP-actin addition at filament barbed ends and have long been presumed to depolymerize at their pointed ends, primarily after filaments undergo “aging” (ATP hydrolysis and P(i) release). The cytosol contains high levels of actin monomers, which favors assembly over di...
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| Опубликовано в: : | J Cell Biol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Rockefeller University Press
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7686915/ https://ncbi.nlm.nih.gov/pubmed/33226418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006022 |
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