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Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization

Cellular actin networks grow by ATP-actin addition at filament barbed ends and have long been presumed to depolymerize at their pointed ends, primarily after filaments undergo “aging” (ATP hydrolysis and P(i) release). The cytosol contains high levels of actin monomers, which favors assembly over di...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Shekhar, Shashank, Hoeprich, Gregory J., Gelles, Jeff, Goode, Bruce L.
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686915/
https://ncbi.nlm.nih.gov/pubmed/33226418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006022
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