Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization

Cellular actin networks grow by ATP-actin addition at filament barbed ends and have long been presumed to depolymerize at their pointed ends, primarily after filaments undergo “aging” (ATP hydrolysis and P(i) release). The cytosol contains high levels of actin monomers, which favors assembly over di...

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Bibliografiset tiedot
Julkaisussa:J Cell Biol
Päätekijät: Shekhar, Shashank, Hoeprich, Gregory J., Gelles, Jeff, Goode, Bruce L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Rockefeller University Press 2020
Aiheet:
Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686915/
https://ncbi.nlm.nih.gov/pubmed/33226418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006022
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