Mammalian twinfilin sequesters ADP-G-actin and caps filament barbed ends: implications in motility

Twinfilins are conserved actin-binding proteins composed of two actin depolymerizing factor homology (ADF-H) domains. Twinfilins are involved in diverse morphological and motile processes, but their mechanism of action has not been elucidated. Here, we show that mammalian twinfilin both sequesters A...

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Bibliographic Details
Main Authors: Helfer, Emmanuèle, Nevalainen, Elisa M, Naumanen, Perttu, Romero, Stéphane, Didry, Dominique, Pantaloni, Dominique, Lappalainen, Pekka, Carlier, Marie-France
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422163/
https://ncbi.nlm.nih.gov/pubmed/16511569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601019
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