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Mammalian twinfilin sequesters ADP-G-actin and caps filament barbed ends: implications in motility
Twinfilins are conserved actin-binding proteins composed of two actin depolymerizing factor homology (ADF-H) domains. Twinfilins are involved in diverse morphological and motile processes, but their mechanism of action has not been elucidated. Here, we show that mammalian twinfilin both sequesters A...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1422163/ https://ncbi.nlm.nih.gov/pubmed/16511569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601019 |
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