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Profilin Interaction with Actin Filament Barbed End Controls Dynamic Instability, Capping, Branching, and Motility
Cell motility and actin homeostasis depend on the control of polarized growth of actin filaments. Profilin, an abundant regulator of actin dynamics, supports filament assembly at barbed ends by binding G-actin. Here, we demonstrate how, by binding and destabilizing filament barbed ends at physiologi...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4729542/ https://ncbi.nlm.nih.gov/pubmed/26812019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.12.024 |
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