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Formin and capping protein together embrace the actin filament in a ménage à trois

Proteins targeting actin filament barbed ends play a pivotal role in motile processes. While formins enhance filament assembly, capping protein (CP) blocks polymerization. On their own, they both bind barbed ends with high affinity and very slow dissociation. Their barbed-end binding is thought to b...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Shekhar, Shashank, Kerleau, Mikael, Kühn, Sonja, Pernier, Julien, Romet-Lemonne, Guillaume, Jégou, Antoine, Carlier, Marie-France
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660058/
https://ncbi.nlm.nih.gov/pubmed/26564775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9730
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