OATP1B1 Polymorphism as a Determinant of Erythromycin Disposition

Previous studies have demonstrated that the pharmacokinetic profile of erythromycin, a probe for CYP3A4 activity, is affected by inhibitors or inducers of hepatic solute carriers. We hypothesized that these interactions are mediated by OATP1B1 (gene symbol, SLCO1B1), a polypeptide expressed on the b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lancaster, CS, Bruun, GH, Peer, CJ, Mikkelsen, TS, Corydon, TJ, Gibson, AA, Hu, S, Orwick, SJ, Mathijssen, RHJ, Figg, WD, Baker, SD, Sparreboom, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478421/
https://ncbi.nlm.nih.gov/pubmed/22990751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2012.106
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados