Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus

Early life experience is associated with long-term effects on behavior and epigenetic programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of both rats and humans. However, it is unlikely that such effects completely capture the evolutionarily conserved epigenetic mechanisms of...

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Hlavní autoři: Suderman, Matthew, McGowan, Patrick O., Sasaki, Aya, Huang, Tony C. T., Hallett, Michael T., Meaney, Michael J., Turecki, Gustavo, Szyf, Moshe
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
Biological Embedding of Early Social Adversity: From Fruit Flies to Kindergartners Sackler Colloquium
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477392/
https://ncbi.nlm.nih.gov/pubmed/23045659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121260109
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