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Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

Maternal care influences hypothalamic-pituitary-adrenal (HPA) function in the rat through epigenetic programming of glucocorticoid receptor expression. In humans, childhood abuse alters HPA stress responses and increases the risk of suicide. We examined epigenetic differences in a neuron-specific gl...

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Detalhes bibliográficos
Main Authors: McGowan, Patrick O, Sasaki, Aya, D’Alessio, Ana C, Dymov, Sergiy, Labonté, Benoit, Szyf, Moshe, Turecki, Gustavo, Meaney, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944040/
https://ncbi.nlm.nih.gov/pubmed/19234457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2270
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