Broad Epigenetic Signature of Maternal Care in the Brain of Adult Rats

BACKGROUND: Maternal care is associated with long-term effects on behavior and epigenetic programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of both rats and humans. In the rat, these effects are reversed by cross-fostering, demonstrating that they are defined by epigenetic r...

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Bibliographic Details
Main Authors: McGowan, Patrick O., Suderman, Matthew, Sasaki, Aya, Huang, Tony C. T., Hallett, Michael, Meaney, Michael J., Szyf, Moshe
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046141/
https://ncbi.nlm.nih.gov/pubmed/21386994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014739
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