Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus

Early life experience is associated with long-term effects on behavior and epigenetic programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of both rats and humans. However, it is unlikely that such effects completely capture the evolutionarily conserved epigenetic mechanisms of...

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Main Authors: Suderman, Matthew, McGowan, Patrick O., Sasaki, Aya, Huang, Tony C. T., Hallett, Michael T., Meaney, Michael J., Turecki, Gustavo, Szyf, Moshe
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Embedding of Early Social Adversity: From Fruit Flies to Kindergartners Sackler Colloquium
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477392/
https://ncbi.nlm.nih.gov/pubmed/23045659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121260109
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