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Design and synthesis of new bicyclic diketopiperazines as scaffolds for receptor probes of structurally diverse functionality()

Diketopiperazines (DKPs) are a common motif in various biologically active natural products, and hence they may be useful scaffolds for the rational design of receptor probes and therapeutic agents. We constructed a new bicyclic scaffold that combines a DKP bridged with a 10-membered ring. In this w...

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Detalhes bibliográficos
Main Authors: Besada, Pedro, Mamedova, Liaman, Thomas, Craig J., Costanzi, Stefano, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476468/
https://ncbi.nlm.nih.gov/pubmed/15889186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b416349d
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