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Mammalian Cell Display for Antibody Engineering

Antibody engineering has generally been carried out by displaying mouse or human antibodies or antibody fragments on the surface of microorganisms (phage, bacteria and yeast). We have shown that mammalian cells can be used to display single chain antibody fragments (scFvs) for affinity maturation. U...

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Detalhes bibliográficos
Main Authors: Ho, Mitchell, Pastan, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475965/
https://ncbi.nlm.nih.gov/pubmed/19252852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-554-1_18
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