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Mammalian Cell Display for Antibody Engineering
Antibody engineering has generally been carried out by displaying mouse or human antibodies or antibody fragments on the surface of microorganisms (phage, bacteria and yeast). We have shown that mammalian cells can be used to display single chain antibody fragments (scFvs) for affinity maturation. U...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475965/ https://ncbi.nlm.nih.gov/pubmed/19252852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-554-1_18 |
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