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Isolation of human monoclonal antibodies by mammalian cell display

Due to their low immunogenicity in patients, humanized or fully human mAbs are becoming increasingly important for the treatment of a growing number of diseases, including cancer, infections, and immune disorders. Here, we describe a technology allowing for the rapid isolation of fully human mAbs. I...

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Bibliographische Detailangaben
Hauptverfasser: Beerli, Roger R., Bauer, Monika, Buser, Regula B., Gwerder, Myriam, Muntwiler, Simone, Maurer, Patrik, Saudan, Philippe, Bachmann, Martin F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567231/
https://ncbi.nlm.nih.gov/pubmed/18812621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805942105
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