Glucagon-Like Peptide-1 Cleavage Product GLP-1(9-36) Amide Rescues Synaptic Plasticity and Memory Deficits in Alzheimer's Disease Model Mice

Glucagon-like peptide-1 (GLP-1) is an endogenous intestinal peptide that enhances glucose-stimulated insulin secretion. Its natural cleavage product GLP-1(9-36)(amide) possesses distinct properties and does not affect insulin secretion. Here we report that pretreatment of hippocampal slices with GLP...

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Hauptverfasser: Ma, Tao, Du, Xueliang, Pick, Joseph E., Sui, Guangzhi, Brownlee, Michael, Klann, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475870/
https://ncbi.nlm.nih.gov/pubmed/23035082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2107-12.2012
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