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Allosteric Modulation of the Activity of the Glucagon-like Peptide-1 (GLP-1) Metabolite GLP-1 9–36 Amide at the GLP-1 Receptor

Glucagon-like peptide-1 (GLP-1) released from intestinal L cells in response to nutrients has many physiological effects but particularly enhances glucose-dependent insulin release through the GLP-1 receptor (GLP-1R). GLP-1 7–36 amide, the predominant circulating active form of GLP-1, is rapidly tru...

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Библиографические подробности
Главные авторы: Li, Naichang, Lu, Jing, Willars, Gary B.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477139/
https://ncbi.nlm.nih.gov/pubmed/23094100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047936
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