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GLP-1(28-36)amide, the Glucagon-like peptide-1 metabolite: friend, foe, or pharmacological folly?

The glucagon-like peptide-1 (GLP-1) axis has emerged as a major therapeutic target for the treatment of type 2 diabetes. GLP-1 mediates its key insulinotropic effects via a G-protein coupled receptor expressed on β-cells and other pancreatic cell types. The insulinotropic activity of GLP-1 is termin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Taing, Meng-Wong, Rose, Felicity J, Whitehead, Jonathan P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051623/
https://ncbi.nlm.nih.gov/pubmed/24940046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S35723
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