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SINE Retrotransposons Cause Epigenetic Reprogramming of Adjacent Gene Promoters

Almost half of the human genome and as much as 40% of the mouse genome is composed of repetitive DNA sequences. The majority of these repeats are retrotransposons of the SINE and LINE families, and such repeats are generally repressed by epigenetic mechanisms. It has been proposed that these element...

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מידע ביבליוגרפי
Main Authors: Estécio, Marcos R.H., Gallegos, Juan, Dekmezian, Mhair, Lu, Yue, Liang, Shoudan, Issa, Jean-Pierre J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475755/
https://ncbi.nlm.nih.gov/pubmed/22952045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0351
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