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Hibris, a Drosophila Nephrin homologue, is required for Presenilin mediated Notch and App-like cleavages
Drosophila Hibris (Hbs), a member of the Nephrin IgG-superfamily, has been implicated in myogenesis and eye patterning. Here, we uncover a role of Hbs in Notch (N)-signaling and γ-secretase processing. Loss of hbs results in classical N-signaling associated phenotypes in Drosophila, including eye pa...
में बचाया:
| मुख्य लेखकों: | , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475182/ https://ncbi.nlm.nih.gov/pubmed/22814602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.04.021 |
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