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Drosophila presenilin Is Required for Neuronal Differentiation and Affects Notch Subcellular Localization and Signaling

Presenilins are a highly conserved family of proteins first identified as causative genes in early onset familial Alzheimer’s disease. Recent studies have suggested a role for presenilins in the Notch-signaling pathway, but their specific function within this pathway remains unclear. Here, we have c...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Guo, Yiquan, Livne-Bar, Izhar, Zhou, Lily, Boulianne, Gabrielle L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783002/
https://ncbi.nlm.nih.gov/pubmed/10493744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-19-08435.1999
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