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Drosophila presenilin Is Required for Neuronal Differentiation and Affects Notch Subcellular Localization and Signaling
Presenilins are a highly conserved family of proteins first identified as causative genes in early onset familial Alzheimer’s disease. Recent studies have suggested a role for presenilins in the Notch-signaling pathway, but their specific function within this pathway remains unclear. Here, we have c...
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| Publié dans: | J Neurosci |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6783002/ https://ncbi.nlm.nih.gov/pubmed/10493744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-19-08435.1999 |
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