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Production and Level of Genetic Stability of an Influenza A Virus Temperature-Sensitive Mutant Containing Two Genes with ts Mutations

Temperature-sensitive (ts) reassortant vaccine strains derived from the A/Udorn/72 ts-1A2 donor virus were not sufficiently stable genetically in humans. We therefore sought to produce a new, more stable donor virus. We had previously identified a stable ts virus with a ts P3 gene and in the current...

詳細記述

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書誌詳細
出版年:Infect Immun
主要な著者: Murphy, Brian R., Markoff, Lewis J., Hosier, Nanette T., Massicot, Judith G., Chanock, Robert M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1982
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347518/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7107005/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.37.1.235-242.1982
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