Production and Level of Genetic Stability of an Influenza A Virus Temperature-Sensitive Mutant Containing Two Genes with ts Mutations

Temperature-sensitive (ts) reassortant vaccine strains derived from the A/Udorn/72 ts-1A2 donor virus were not sufficiently stable genetically in humans. We therefore sought to produce a new, more stable donor virus. We had previously identified a stable ts virus with a ts P3 gene and in the current...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Murphy, Brian R., Markoff, Lewis J., Hosier, Nanette T., Massicot, Judith G., Chanock, Robert M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1982
Fag:	Viral Infections and Immunity
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347518/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7107005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.37.1.235-242.1982
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