Biosynthesis of 3-Iodothyronamine (T(1)AM) Is Dependent on the Sodium-Iodide Symporter and Thyroperoxidase but Does Not Involve Extrathyroidal Metabolism of T(4)

3-Iodothyronamine (T(1)AM) is an endogenous thyroid hormone derivative with unknown biosynthetic origins. Structural similarities have led to the hypothesis that T(1)AM is an extrathyroidal metabolite of T(4). This study uses an isotope-labeled T(4) [heavy-T(4) (H-T(4))] that can be distinguished fr...

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Bibliografski detalji
Glavni autori: Hackenmueller, Sarah A., Marchini, Maja, Saba, Alessandro, Zucchi, Riccardo, Scanlan, Thomas S.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2012
Teme:
Thyroid-TRH-TSH
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473208/
https://ncbi.nlm.nih.gov/pubmed/22948220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1254
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