Biosynthesis of 3-Iodothyronamine (T(1)AM) Is Dependent on the Sodium-Iodide Symporter and Thyroperoxidase but Does Not Involve Extrathyroidal Metabolism of T(4)

3-Iodothyronamine (T(1)AM) is an endogenous thyroid hormone derivative with unknown biosynthetic origins. Structural similarities have led to the hypothesis that T(1)AM is an extrathyroidal metabolite of T(4). This study uses an isotope-labeled T(4) [heavy-T(4) (H-T(4))] that can be distinguished fr...

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Detaylı Bibliyografya
Asıl Yazarlar: Hackenmueller, Sarah A., Marchini, Maja, Saba, Alessandro, Zucchi, Riccardo, Scanlan, Thomas S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2012
Konular:
Thyroid-TRH-TSH
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473208/
https://ncbi.nlm.nih.gov/pubmed/22948220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1254
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