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Structure and Stability of Duplex DNA Containing (5’S)-5’,8-Cyclo-2’-Deoxyadenosine: An Oxidatively-generated Lesion Repaired by NER

Cellular respiration and ionizing radiation generate 5’,8-cyclo-2’-deoxyribonucleosides, an especial type of DNA damage that involves two modifications in the same nucleotide. These lesions evade the action of base excision glycosylases and their removal is a function of the nucleotide excision repa...

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Autors principals: Zaliznyak, Tatiana, Lukin, Mark, Santos, Carlos de los
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472033/
https://ncbi.nlm.nih.gov/pubmed/22928555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300193k
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