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Structure and Stability of Duplex DNA Containing (5’S)-5’,8-Cyclo-2’-Deoxyadenosine: An Oxidatively-generated Lesion Repaired by NER
Cellular respiration and ionizing radiation generate 5’,8-cyclo-2’-deoxyribonucleosides, an especial type of DNA damage that involves two modifications in the same nucleotide. These lesions evade the action of base excision glycosylases and their removal is a function of the nucleotide excision repa...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3472033/ https://ncbi.nlm.nih.gov/pubmed/22928555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300193k |
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