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Simple and efficient purification of Escherichia coli DNA polymerase V: Cofactor requirements for optimal activity and processivity in vitro

Most damage induced mutagenesis in Escherichia coli is dependent upon the [Formula: see text] protein complex, which comprises DNA polymerase V (pol V). Biochemical characterization of pol V has been hindered by the fact that the enzyme is notoriously difficult to purify, largely because overproduce...

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Detalhes bibliográficos
Main Authors: Karata, Kiyonobu, Vaisman, Alexandra, Goodman, Myron F., Woodgate, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471214/
https://ncbi.nlm.nih.gov/pubmed/22341652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.01.012
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