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Simple and efficient purification of Escherichia coli DNA polymerase V: Cofactor requirements for optimal activity and processivity in vitro

Most damage induced mutagenesis in Escherichia coli is dependent upon the [Formula: see text] protein complex, which comprises DNA polymerase V (pol V). Biochemical characterization of pol V has been hindered by the fact that the enzyme is notoriously difficult to purify, largely because overproduce...

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Hlavní autoři: Karata, Kiyonobu, Vaisman, Alexandra, Goodman, Myron F., Woodgate, Roger
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471214/
https://ncbi.nlm.nih.gov/pubmed/22341652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.01.012
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