Mechanism of Growth Inhibition of Prostate Cancer Xenografts by Valproic Acid

Valproic Acid (VPA), a histone deacetylase inhibitor, has been demonstrated to cause a marked decrease in proliferation of prostate cancer (PCa) cells in vitro and a significant reduction in tumor volume in vivo. The goal of this study is to better understand the VPA-induced growth inhibition in viv...

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Detalhes bibliográficos
Main Authors: Sidana, Abhinav, Wang, Muwen, Shabbeer, Shabana, Chowdhury, Wasim H., Netto, George, Lupold, Shawn E., Carducci, Michael, Rodriguez, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471003/
https://ncbi.nlm.nih.gov/pubmed/23093837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/180363
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