Does Valproic Acid Induce Neuroendocrine Differentiation in Prostate Cancer?

Valproic Acid (VPA) is a histone deacetylase inhibitor that holds promise for cancer therapy. Here, we investigate whether VPA treatment induces neuroendocrine differentiation of Prostate Cancer (PCa). A tissue microarray of VPA-treated and untreated tumor xenografts and cell lines of human PCa (LNC...

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Detalhes bibliográficos
Main Authors: Sidana, Abhinav, Wang, Muwen, Chowdhury, Wasim H., Toubaji, Antoun, Shabbeer, Shabana, Netto, George, Carducci, Michael, Lupold, Shawn E., Rodriguez, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963803/
https://ncbi.nlm.nih.gov/pubmed/20981253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/607480
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