Valproic acid induces autophagy by suppressing the Akt/mTOR pathway in human prostate cancer cells

Previous studies have demonstrated that the chronic administration of valproic acid (VPA) suppresses angiogenesis in vivo; however, the mechanisms implicated in VPA-induced autophagy remain unclear. The current study aimed to assess VPA-induced autophagy in three prostate cancer cell lines (PC3, DU1...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Xia, Qinghua, Zheng, Yi, Jiang, Wei, Huang, Zhongxian, Wang, Muwen, Rodriguez, Ronald, Jin, Xunbo
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2016
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998110/
https://ncbi.nlm.nih.gov/pubmed/27588130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4880
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