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Autophagy activation promotes bevacizumab resistance in glioblastoma by suppressing Akt/mTOR signaling pathway

Glioblastomas are the most common primary and malignant brain tumors. The standard therapy includes surgery and radiotherapy plus chemotherapy, with additional bevacizumab to block the angiogenesis in tumors. However, the ever-growing tolerance of glioblastomas to chemotherapeutic drugs impairs the...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Huang, He, Song, Jian, Liu, Zheng, Pan, Li, Xu, Guozheng
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774481/
https://ncbi.nlm.nih.gov/pubmed/29434840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7446
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